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Small molecules

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

Peter Reinhardt, Michael Glatza, Kathrin Hemmer, Yaroslav Tsytsyura, Cora S. Thiel, Susanne Höing, Sören Moritz, Juan A. Parga, Lydia Wagner, Jan M. Bruder, Guangming Wu, Benjamin Schmid, Albrecht Röpke, Jürgen Klingauf, Jens C. Schwamborn, Thomas Gasser, Hans R. Schöler, Jared Sterneckert

published 22 Mar 2013

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A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN)

Joshua A. Sommers, Tomasz Kulikowicz, Deborah L. Croteau, Thomas Dexheimer, Dorjbal Dorjsuren, Ajit Jadhav, David J. Maloney, Anton Simeonov, Vilhelm A. Bohr, Robert M. Brosh Jr.

published 09 Jan 2019

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Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells

Jijun Hao, Marie A. Daleo, Clare K. Murphy, Paul B. Yu, Joshua N. Ho, Jianyong Hu, Randall T. Peterson, Antonis K. Hatzopoulos, Charles C. Hong

published 06 Aug 2008

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Multiplex Cytological Profiling Assay to Measure Diverse Cellular States

Sigrun M. Gustafsdottir, Vebjorn Ljosa, Katherine L. Sokolnicki, J. Anthony Wilson, Deepika Walpita, Melissa M. Kemp, Kathleen Petri Seiler, Hyman A. Carrel, Todd R. Golub, Stuart L. Schreiber, Paul A. Clemons, Anne E. Carpenter, Alykhan F. Shamji

published 02 Dec 2013

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Promotion of Prescription Drugs to Consumers and Providers, 2001–2010

Rachel Kornfield, Julie Donohue, Ernst R. Berndt, G. Caleb Alexander

published 04 Mar 2013

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A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

Melanie Gertz, Giang Thi Tuyet Nguyen, Frank Fischer, Benjamin Suenkel, Christine Schlicker, Benjamin Fränzel, Jana Tomaschewski, Firouzeh Aladini, Christian Becker, Dirk Wolters, Clemens Steegborn

published 21 Nov 2012

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Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2

Sidhartha Chaudhury, Monica Berrondo, Brian D. Weitzner, Pravin Muthu, Hannah Bergman, Jeffrey J. Gray

published 02 Aug 2011

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Efficient Feeder-Free Episomal Reprogramming with Small Molecules

Junying Yu, Kevin Fongching Chau, Maxim A. Vodyanik, Jinlan Jiang, Yong Jiang

published 01 Mar 2011

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Ligand Pose and Orientational Sampling in Molecular Docking

Ryan G. Coleman, Michael Carchia, Teague Sterling, John J. Irwin, Brian K. Shoichet

published 01 Oct 2013

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A Fluorescence-Based Thermal Shift Assay Identifies Inhibitors of Mitogen Activated Protein Kinase Kinase 4

Sankar N. Krishna, Chi-Hao Luan, Rama K. Mishra, Li Xu, Karl A. Scheidt, Wayne F. Anderson, Raymond C. Bergan

published 05 Dec 2013

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Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

Chew Hooi Wong, Kartini Bte Iskandar, Sanjiv Kumar Yadav, Jayshree L. Hirpara, Thomas Loh, Shazib Pervaiz

published 02 Apr 2010

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Timelines of translational science: From technology initiation to FDA approval

Laura M. McNamee, Michael Jay Walsh, Fred D. Ledley

published 08 May 2017

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Identification of Small Molecule Activators of BMP Signaling

Karen Vrijens, Wenwei Lin, Jimmy Cui, Dana Farmer, Jonathan Low, Elodie Pronier, Fu-Yue Zeng, Anang A. Shelat, Kiplin Guy, Michael R. Taylor, Taosheng Chen, Martine F. Roussel

published 19 Mar 2013

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