Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Phase III clinical investigation

Evaluating the efficacy and safety of mavacamten in hypertrophic cardiomyopathy: A systematic review and meta-analysis focusing on qualitative assessment, biomarkers, and cardiac imaging

Rahul Vyas, Viraj Panchal, Shubhika Jain, Manush Sondhi, Mansunderbir Singh, Keerthish Jaisingh, Sahith Reddy Thotamgari, Anuj Thakre, Kalgi Modi

published 18 Apr 2024

Loading metrics information...

Metrics unavailable. Please check back later.

Efficacy of hyperthermic intraperitoneal chemotherapy in colorectal cancer: A phase I and III open label randomized controlled registry-based clinical trial protocol

Lana Ghanipour, Gabriella Jansson Palmer, Per J. Nilsson, Caroline Nordenvall, Jan-Erik Frödin, Elinor Bexe Lindskog, Dan Asplund, Torbjörn Swartling, Wilhelm Graf, Helgi Birgisson, Ingvar Syk, Victor Verwaal, Jenny Brändstedt, Peter H. Cashin

published 04 Mar 2024

Loading metrics information...

Metrics unavailable. Please check back later.

Measuring the efficacy of a vaccine during an epidemic

Antonio Scala, Pierpaolo Cavallo

published 14 Sep 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Gulf war illness inflammation reduction trial: A phase 2 randomized controlled trial of low-dose prednisone chronotherapy, effects on health-related quality of life

Ronald R. Bach, Rebecca R. Rudquist

published 15 Jun 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial)

Mariana S. Sousa, Peter Martin, Miriam J. Johnson, Michael Lind, Matthew Maddocks, Alex Bullock, Meera Agar, Sungwon Chang, Slavica Kochovska, Irina Kinchin, Deidre Morgan, Belinda Fazekas, Valentina Razmovski-Naumovski, Jessica T. Lee, Malinda Itchins, Victoria Bray, David C. Currow

published 17 May 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Time-dependent vaccine efficacy estimation quantified by a mathematical model

Jennifer Loria, Vinicius V. L. Albani, Francisco A. B. Coutinho, Dimas T. Covas, Claudio J. Struchiner, Jorge P. Zubelli, Eduardo Massad

published 11 May 2023

Loading metrics information...

Metrics unavailable. Please check back later.

RWD-derived response in multiple myeloma

Tao Xu, James Roose, Mellissa Williamson, Ahmed Sawas, Wan-Jen Hong, Huan Jin, Kathleen Maignan, Alberto Rocci, Kasra Yousefi, Shaji Kumar, Stefka Tyanova

published 11 May 2023

Loading metrics information...

Metrics unavailable. Please check back later.

What is the ‘voltage drop’ when an effective health promoting intervention for older adults—Choose to Move (Phase 3)—Is implemented at broad scale?

Heather A. McKay, Heather M. Macdonald, Lindsay Nettlefold, Katie Weatherson, Samantha M. Gray, Adrian Bauman, Karim M. Khan, Joanie Sims Gould

published 05 May 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Identifying optimal first-line immune checkpoint inhibitors based regiments for advanced non-small cell lung cancer without oncogenic driver mutations: A systematic review and network meta-analysis

Tingting Liu, Sijia Wu, Weiwei Fang, Hongkai Li, Lili Su, Guiye Qi, Huaichen Li, Yao Liu

published 18 Apr 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Use of “The Knowledge-to-Action Framework” for the implementation of evidence-based nursing in child and family care: Study protocol

Cânia P. Torres, Francisco J. Mendes, Maria Barbieri-Figueiredo

published 31 Mar 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Study protocol for a phase III randomised controlled trial of Sailuotong (SLT) for vascular dementia and Alzheimer’s disease with cerebrovascular disease

Diana Karamacoska, Daniel K. Y. Chan, Isabella Leung, Jian-xun Liu, Henry Brodaty, Paul P. Fahey, Alan Bensoussan, Dennis H. Chang

published 15 Mar 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Designing an exploratory phase 2b platform trial in NASH with correlated, co-primary binary endpoints

Elias Laurin Meyer, Peter Mesenbrink, Nicholas A. Di Prospero, Juan M. Pericàs, Ekkehard Glimm, Vlad Ratziu, Elena Sena, Franz König, on behalf of the EU-PEARL NASH Investigators

published 09 Mar 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Reduction strategies for inpatient oral third-generation cephalosporins at a cancer center: An interrupted time-series analysis

Naoya Itoh, Takanori Kawabata, Nana Akazawa, Daichi Kawamura, Hiromi Murakami, Yuichi Ishibana, Eiichi N. Kodama, Norio Ohmagari

published 09 Feb 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Tweets by @plosone

Advertisement

Create a weekly email alert for: Phase III clinical investigation

You can change these options by clicking profile then "Alerts and Notifications"