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Ion channels

Transient plasma membrane disruption induced calcium waves in mouse and human corneal epithelial cells

Zhong Chen, Xiaowen Lu, Mitchell A. Watsky

published 17 Apr 2024

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BK ZERO isoform HEK293 stably transfected cell lines differing 3’UTRs to assess miR-9 regulation

Katherine Cordero Padilla, Gerardo Alvarado Monefeldt, Adriel Guevárez Galán, Hector G. Marrero, Mario E. Lloret-Torres, Cristina Velázquez-Marrero

published 19 Mar 2024

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Equilibrium landscape of ingress/egress channels and gating residues of the Cytochrome P450 3A4

Edward Michael Ackad, Laurence Biggers, Mary Meister, Maria Kontoyianni

published 18 Mar 2024

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The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Na_v1.5

Oksana Iamshanova, Anne-Flore Hämmerli, Elise Ramaye, Arbresh Seljmani, Daniela Ross-Kaschitza, Noëlia Schärz, Maria Essers, Sabrina Guichard, Jean-Sébastien Rougier, Hugues Abriel

published 07 Mar 2024

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Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca²⁺ entry in HEK293 cells

Katherine Norman, Karen E. Hemmings, Heba Shawer, Hollie L. Appleby, Alan J. Burnett, Nurasyikin Hamzah, Rajendra Gosain, Emily M. Woodhouse, David J. Beech, Richard Foster, Marc A. Bailey

published 23 Jan 2024

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In silico analysis of TRPM4 variants of unknown clinical significance

Svetlana I. Tarnovskaya, Anna A. Kostareva, Boris S. Zhorov

published 15 Dec 2023

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Differential activation of mouse and human Panx1 channel variants

Antonio Cibelli, Preeti Dohare, David C. Spray, Eliana Scemes

published 15 Dec 2023

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Estrogen inhibits colonic smooth muscle contractions by regulating BKβ1 signaling

Jing Wen, Yu Zhao, Cheng Huang, Shengjie Li, Peidong Li, Yu Zhou, Zaihua Yan, Guangjun Zhang

published 10 Nov 2023

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Acute inhibition of acid sensing ion channel 1a after spinal cord injury selectively affects excitatory synaptic transmission, but not intrinsic membrane properties, in deep dorsal horn interneurons

Victoria S. Foster, Natalie Saez, Glenn F. King, Michelle M. Rank

published 08 Nov 2023

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Mechanisms underlying the antiarrhythmic effect of ARumenamide-787 in experimental models of the J wave syndromes and hypothermia

José M. Di Diego, Hector Barajas-Martinez, Robert Cox, Victoria M. Robinson, Joseph Jung, Mohamed Fouda, Bence Patocskai, Mena Abdelsayed, Peter C. Ruben, Charles Antzelevitch

published 09 May 2023

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Homeostasis at different backgrounds: The roles of overlayed feedback structures in vertebrate photoadaptation

Jonas V. Grini, Melissa Nygård, Peter Ruoff

published 28 Apr 2023

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L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum

Anmol Kumar, Stefan Mutter, Erika B. Parente, Valma Harjutsalo, Raija Lithovius, Sinnakaruppan Mathavan, Markku Lehto, Timo P. Hiltunen, Kimmo K. Kontula, Per-Henrik Groop

published 13 Apr 2023

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Benzonatate as a local anesthetic

Anna McGuire, Claire A. Ostertag-Hill, Gil Aizik, Yang Li, Daniel S. Kohane

published 12 Apr 2023

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