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Cancer genetics

Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells

Junichi Soh, Naoki Okumura, William W. Lockwood, Hiromasa Yamamoto, Hisayuki Shigematsu, Wei Zhang, Raj Chari, David S. Shames, Ximing Tang, Calum MacAulay, Marileila Varella-Garcia, Tõnu Vooder, Ignacio I. Wistuba, Stephen Lam, Rolf Brekken, Shinichi Toyooka, John D. Minna, Wan L. Lam, Adi F. Gazdar

published 14 Oct 2009

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Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes

Vonn Walter, Xiaoying Yin, Matthew D. Wilkerson, Christopher R. Cabanski, Ni Zhao, Ying Du, Mei Kim Ang, Michele C. Hayward, Ashley H. Salazar, Katherine A. Hoadley, Karen Fritchie, Charles G. Sailey, Mark C. Weissler, William W. Shockley, Adam M. Zanation, Trevor Hackman, Leigh B. Thorne, William D. Funkhouser, Kenneth L. Muldrew, Andrew F. Olshan, Scott H. Randell, Fred A. Wright, Carol G. Shores, D. Neil Hayes

published 22 Feb 2013

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Identification of Tumor Suppressors and Oncogenes from Genomic and Epigenetic Features in Ovarian Cancer

Kazimierz O. Wrzeszczynski, Vinay Varadan, James Byrnes, Elena Lum, Sitharthan Kamalakaran, Douglas A. Levine, Nevenka Dimitrova, Michael Q. Zhang, Robert Lucito

published 08 Dec 2011

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SOX2 Gene Regulates the Transcriptional Network of Oncogenes and Affects Tumorigenesis of Human Lung Cancer Cells

Si Chen, Yingxi Xu, Yanan Chen, Xuefei Li, Wenjun Mou, Lina Wang, Yanhua Liu, Ralph A. Reisfeld, Rong Xiang, Dan Lv, Na Li

published 15 May 2012

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Human MicroRNA Oncogenes and Tumor Suppressors Show Significantly Different Biological Patterns: From Functions to Targets

Dong Wang, Chengxiang Qiu, Haijun Zhang, Juan Wang, Qinghua Cui, Yuxin Yin

published 30 Sep 2010

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Comparison of the Cancer Gene Targeting and Biochemical Selectivities of All Targeted Kinase Inhibitors Approved for Clinical Use

Joost C. M. Uitdehaag, Jeroen A. D. M. de Roos, Antoon M. van Doornmalen, Martine B. W. Prinsen, Jos de Man, Yoshinori Tanizawa, Yusuke Kawase, Kohichiro Yoshino, Rogier C. Buijsman, Guido J. R. Zaman

published 20 Mar 2014

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Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate

Benjamin W. Darbro, Rohini Singh, M. Bridget Zimmerman, Vinit B. Mahajan, Alexander G. Bassuk

published 02 Mar 2016

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Identification and Pathway Analysis of microRNAs with No Previous Involvement in Breast Cancer

Sandra Romero-Cordoba, Sergio Rodriguez-Cuevas, Rosa Rebollar-Vega, Valeria Quintanar-Jurado, Antonio Maffuz-Aziz, Gerardo Jimenez-Sanchez, Veronica Bautista-Piña, Rocio Arellano-Llamas, Alfredo Hidalgo-Miranda

published 16 Mar 2012

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Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

Jared Wallace, Ruozhen Hu, Timothy L. Mosbruger, Timothy J. Dahlem, W. Zac Stephens, Dinesh S. Rao, June L. Round, Ryan M. O’Connell

published 15 Apr 2016

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SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas

Thomas Hussenet, Soraya Dali, Julien Exinger, Ben Monga, Bernard Jost, Doulaye Dembelé, Nadine Martinet, Christelle Thibault, Joerg Huelsken, Elisabeth Brambilla, Stanislas du Manoir

published 29 Jan 2010

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A Comprehensive Characterization of Genome-Wide Copy Number Aberrations in Colorectal Cancer Reveals Novel Oncogenes and Patterns of Alterations

Tao Xie, Giovanni d’ Ario, John R. Lamb, Eric Martin, Kai Wang, Sabine Tejpar, Mauro Delorenzi, Fred T. Bosman, Arnaud D. Roth, Pu Yan, Stephanie Bougel, Antonio Fabio Di Narzo, Vlad Popovici, Eva Budinská, Mao Mao, Scott L. Weinrich, Paul A. Rejto, J. Graeme Hodgson

published 31 Jul 2012

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Copy Number Analysis Identifies Novel Interactions Between Genomic Loci in Ovarian Cancer

Kylie L. Gorringe, Joshy George, Michael S. Anglesio, Manasa Ramakrishna, Dariush Etemadmoghadam, Prue Cowin, Anita Sridhar, Louise H. Williams, Samantha E. Boyle, Nozomu Yanaihara, Aikou Okamoto, Mitsuyoshi Urashima, Australian Ovarian Cancer Study , Gordon K. Smyth, Ian G. Campbell, David D. L. Bowtell

published 10 Sep 2010

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Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces

H. Billur Engin, Jason F. Kreisberg, Hannah Carter

published 04 Apr 2016

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