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Animal models

Aging in zebrafish is associated with reduced locomotor activity and strain dependent changes in bottom dwelling and thigmotaxis

Jacob Hudock, Justin W. Kenney

Control of acute myeloid leukemia and generation of immune memory in vivo using AMV564, a bivalent bispecific CD33 x CD3 T cell engager

Linda G. Eissenberg, Julie K. Ritchey, [ ... ], John F. DiPersio

Zhilong Huoxue Tongyu capsule improves myocardial ischemia/reperfusion injury via the PI3K/AKT/Nrf2 axis

Xiaoping Zhao, Fang Yang, [ ... ], Gong Chen

pH-responsive targeted nanoparticles release ERK-inhibitor in the hypoxic zone and sensitize free gemcitabine in mutant K-Ras-addicted pancreatic cancer cells and mouse model

Debasmita Dutta, Priyanka Ray, [ ... ], Sushanta K. Banerjee

Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma

Imani Bijou, Yang Liu, [ ... ], Jin Wang

The effect of common paralytic agents used for fluorescence imaging on redox tone and ATP levels in Caenorhabditis elegans

Katherine S. Morton, Ashlyn K. Wahl, Joel N. Meyer

Effect of SARS-CoV-2 S protein on the proteolytic cleavage of the epithelial Na⁺ channel ENaC

Germán Ricardo Magaña-Ávila, Erika Moreno, [ ... ], María Castañeda-Bueno

Increased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis

Luciano Adorini, Kristoffer Rigbolt, [ ... ], Mary Erickson

Rabbit intakes and predictors of their length of stay in animal shelters in British Columbia, Canada

Ashley Sum Yin U., Cheng Yu Hou, Alexandra Protopopova

Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons

Claudia I. Perez, Jorge Luis-Islas, [ ... ], Ranier Gutierrez

DFMG decreases angiogenesis to uphold plaque stability by inhibiting the TLR4/VEGF pathway in mice

Pingjuan Bai, Xueping Xiang, [ ... ], Lesai Li

The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products

Jeremy Garb, Gil Amitai, [ ... ], Rotem Sorek

Predation risk of the sea urchin Paracentrotus lividus juveniles in an overfished area reveal system stability mechanisms and restocking challenges

Federico Pinna, Nicola Fois, [ ... ], Giulia Ceccherelli

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