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Microsomes

Pharmacokinetic profile of oral and subcutaneous administration of paracetamol in the koala (Phascolarctos cinereus) and prediction of its analgesic efficacy

Merran Govendir, Larry Vogelnest, [ ... ], Benjamin Kimble

Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization

Stephanie E. Martinez, Amit V. Pandey, [ ... ], Michael H. Court

Impact of valproic acid on busulfan pharmacokinetics: In vitro assessment of potential drug-drug interaction

Bashayer F. Al-Enezi, Nada Al-Hasawi, Kamal M. Matar

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn²⁺-dependent amidases

Jae Kyo Yi, Ruijuan Xu, [ ... ], Cungui Mao

Glycyrrhiza uralensis promote the metabolism of toxic components of Aconitum carmichaeli by CYP3A and alleviate the development of chronic heart failure

Lulu Ni, Ping Miao, [ ... ], Su Tu

Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis

Saumel Pérez-Rodriguez, María de Jesús Ramírez-Lira, [ ... ], Norma A. Valdez-Cruz

Hydrogenosomal tail-anchored proteins are targeted to both mitochondria and ER upon their expression in yeast cells

Andrè Ferdigg, Kai S. Dimmer, Doron Rapaport, Daniela G. Vitali

In vitro hepatic metabolism of mefloquine using microsomes from cats, dogs and the common brush-tailed possum (Trichosurus vulpecula)

Aaron Michael Izes, Benjamin Kimble, Jacqueline Marie Norris, Merran Govendir

Functions of mountain pine beetle cytochromes P450 CYP6DJ1, CYP6BW1 and CYP6BW3 in the oxidation of pine monoterpenes and diterpene resin acids

Christine C. Chiu, Christopher I. Keeling, Hannah M. Henderson, Joerg Bohlmann

The N-terminus of Sec61p plays key roles in ER protein import and ERAD

Francesco Elia, Lalitha Yadhanapudi, Thomas Tretter, Karin Römisch

Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability

Ali S. Abdelhameed, Adnan A. Kadi, Mohamed W. Attwa, Haitham AlRabiah

Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation

Fabio Pereira, Mandy Rettel, [ ... ], Karin Römisch

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

Wolfgang Klein, Claudia Rutz, [ ... ], Ralf Schülein

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