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Genetics

Frailty and risk of systemic atherosclerosis: A bidirectional Mendelian randomization study

Liugang Xu, Yajun Wang, Hongyun Ji, Wei Du, Chunhui You, Jin Chen, Jianyu Jiang, Yisi Shan, Qian Pan, Ruihong Cao

published 23 May 2024

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Metabolomics and transcriptomics reveal the mechanism of alkaloid synthesis in Corydalis yanhusuo bulbs

Xiao Zhao, Yuan Pan, Jun Tan, Hui Lv, Yu Wang, Da-xia Chen

published 23 May 2024

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Protocol for the establishment of a serine integrase-based platform for functional validation of genetic switch controllers in eukaryotic cells

Marco A. de Oliveira, Lilian H. Florentino, Thais T. Sales, Rayane N. Lima, Luciana R. C. Barros, Cintia G. Limia, Mariana S. M. Almeida, Maria L. Robledo, Leila M. G. Barros, Eduardo O. Melo, Daniela M. Bittencourt, Stevens K. Rehen, Martín H. Bonamino, Elibio Rech

published 23 May 2024

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Characterization of Argonaute-containing protein complexes in Leishmania-infected human macrophages

Atieh Moradimotlagh, Harsimran Kaur Brar, Stella Chen, Kyung-Mee Moon, Leonard J. Foster, Neil Reiner, Devki Nandan

published 23 May 2024

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Environmental metabolomics characterization of modern stromatolites and annotation of ibhayipeptolides

George F. Neuhaus, Allegra T. Aron, Eric W. Isemonger, Daniel Petras, Samantha C. Waterworth, Luthando S. Madonsela, Emily C. Gentry, Xavier Siwe Noundou, Jarmo-Charles J Kalinski, Alexandros Polyzois, Julius C. Habiyaremye, Margaret A. Redick, Jason C. Kwan, Rosemary A. Dorrington, Pieter C. Dorrestein, Kerry L. McPhail

published 23 May 2024

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Programmed cell death-1 is involved with peripheral blood immune cell profiles in patients with hepatitis C virus antiviral therapy

Miyabi Miura, Michiko Nishino, Kazunori Kawaguchi, Shihui Li, Tetsuro Shimakami, Toshikatsu Tamai, Hidetoshi Nakagawa, Takeshi Terashima, Noriho Iida, Hajime Takatori, Kuniaki Arai, Yoshio Sakai, Tatsuya Yamashita, Masao Honda, Shuichi Kaneko, Eishiro Mizukoshi, Taro Yamashita

published 23 May 2024

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The monsoon-associated equine South African pointy mosquito ‘Aedes caballus’; the first comprehensive record from southeastern Iran with a description of ecological, morphological, and molecular aspects

Jalil Nejati, Shahyad Azari-Hamidian, Mohammad Ali Oshaghi, Hassan Vatandoost, Vanessa L. White, Seyed H. Moosa-Kazemi, Rubén Bueno-Marí, Ahmad A. Hanafi-Bojd, Nancy M. Endersby-Harshman, Jason K. Axford, Fateh Karimian, Mona Koosha, Nayyereh Choubdar, Ary A. Hoffmann

published 23 May 2024

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Intronic miR-6741-3p targets the oncogene SRSF3: Implications for oral squamous cell carcinoma pathogenesis

Dhanashree Anil More, Nivedita Singh, Radha Mishra, Harsha Pulakkat Muralidharan, Kodaganur Srinivas Gopinath, Champaka Gopal, Arun Kumar

published 23 May 2024

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Molecular regulation of PPARγ/RXRα signaling by the novel cofactor ZFP407

Alyssa Charrier, Jeremiah Ockunzzi, Leighanne Main, Siddharth V. Ghanta, David A. Buchner

published 23 May 2024

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Species-specific dynamics may cause deviations from general biogeographical predictions – evidence from a population genomics study of a New Guinean endemic passerine bird family (Melampittidae)

Ingo A. Müller, Filip Thörn, Samyuktha Rajan, Per G. P. Ericson, John P. Dumbacher, Gibson Maiah, Mozes P. K. Blom, Knud A. Jønsson, Martin Irestedt

published 23 May 2024

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KLRG1-expressing CD8+ T cells are exhausted and polyfunctional in patients with chronic hepatitis B

Li Wang, Fangli Liao, Liping Yang, Linshan Jiang, Liang Duan, Bo Wang, Di Mu, Juan Chen, Ying Huang, Qin Hu, Weixian Chen

published 22 May 2024

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Cigarette smoke sustains immunosuppressive microenvironment inducing M2 macrophage polarization and viability in lung cancer settings

Francesca Bianchi, Valentino Le Noci, Giancarla Bernardo, Nicoletta Gagliano, Graziano Colombo, Michele Sommariva, Michele Palazzo, Isabella Dalle-Donne, Aldo Milzani, Serenella Pupa, Elda Tagliabue, Lucia Sfondrini

published 22 May 2024

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Loss of the yeast transporter Agp2 upregulates the pleiotropic drug-resistant pump Pdr5 and confers resistance to the protein synthesis inhibitor cycloheximide

Yusra Manzoor, Mustapha Aouida, Ramya Ramadoss, Balasubramanian Moovarkumudalvan, Nisar Ahmed, Abdallah Alhaj Sulaiman, Ashima Mohanty, Reem Ali, Borbala Mifsud, Dindial Ramotar

published 22 May 2024

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