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Figure 1. Schematic organization of (A) previously identified, testicular sAC transcripts and (B) the newly identified somatic sAC transcript.

Boxes denote exons. C1 and C2 refer to the two catalytic domains. Red exons contain stop codons. (A) sAC_fl is encoded by all known coding exons (32), and sAC_t is generated by skipping exon 12. Yellow exons (2-4) are removed in the Sacy^tm1Lex allele. Arrows indicate approximate locations of epitopes for the indicated monoclonal antibodies (R40, R21, and R37). (B) Somatic sAC transcripts derive from a unique start site upstream of exon 5 and continue through at least exon 16 to an unknown stop.