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Figure 1. Definition of Topology S loci in (a) A. oryzae, (b) A. fumigatus, and (c) A. nidulans.

Yellow boxes indicate the genes that are orthologous in the three species. The red box contains the extra paralog (labeled AO2, AFU2 or AN2). Loci having Topology S were identified in each species by an automated process without the use of an outgroup, but the root of the tree is likely to lie on the upper (longest) branch.