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Research Article

Application of Detergents or High Hydrostatic Pressure as Decellularization Processes in Uterine Tissues and Their Subsequent Effects on In Vivo Uterine Regeneration in Murine Models

  • Erna G. Santoso equal contributor,

    equal contributor Contributed equally to this work with: Erna G. Santoso, Keita Yoshida

    Affiliation: Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan

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  • Keita Yoshida equal contributor,

    equal contributor Contributed equally to this work with: Erna G. Santoso, Keita Yoshida

    Affiliation: Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan

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  • Yasushi Hirota,

    Affiliation: Department of Obstetrics and Gynecology, School of Medicine, The University of Tokyo, Tokyo, Japan

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  • Masanori Aizawa,

    Affiliation: Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan

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  • Osamu Yoshino,

    Affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan

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  • Akio Kishida,

    Affiliation: Department of Material-based Medical Engineering, Division of Biofunctional Restoration, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

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  • Yutaka Osuga,

    Affiliation: Department of Obstetrics and Gynecology, School of Medicine, The University of Tokyo, Tokyo, Japan

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  • Shigeru Saito,

    Affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan

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  • Takashi Ushida,

    Affiliations: Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan, Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan

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  • Katsuko S. Furukawa mail

    furukawa@mech.t.u-tokyo.ac.jp

    Affiliations: Department of Mechanical Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan, Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan

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  • Published: July 24, 2014
  • DOI: 10.1371/journal.pone.0103201

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