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Open Access
Peer-reviewed
Research Article
Mice Fed Rapamycin Have an Increase in Lifespan Associated with Major Changes in the Liver Transcriptome
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Wilson C. Fok,
Affiliation Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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Yidong Chen,
Affiliations Department of Epidemiology & Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Cancer Therapy and Research Center, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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Alex Bokov,
Affiliations Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Epidemiology & Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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Yiqiang Zhang,
Affiliations Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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Adam B. Salmon,
Affiliations Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Research Service and Geriatric Research Education and Clinical Center, Audie Murphy VA Hospital (STVHCS), San Antonio, Texas, United States of America
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Vivian Diaz,
Affiliation Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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Martin Javors,
Affiliation Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
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William H. Wood 3rd,
Affiliation National Institute on Aging, Baltimore, Maryland, United States of America
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Yongqing Zhang,
Affiliation National Institute on Aging, Baltimore, Maryland, United States of America
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Kevin G. Becker,
Affiliation National Institute on Aging, Baltimore, Maryland, United States of America
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Viviana I. Pérez,
Affiliation Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, United States of America
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Arlan Richardson
* E-mail: richardsona@uthscsa.edu
Affiliations Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Research Service and Geriatric Research Education and Clinical Center, Audie Murphy VA Hospital (STVHCS), San Antonio, Texas, United States of America
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Mice Fed Rapamycin Have an Increase in Lifespan Associated with Major Changes in the Liver Transcriptome
- Wilson C. Fok,
- Yidong Chen,
- Alex Bokov,
- Yiqiang Zhang,
- Adam B. Salmon,
- Vivian Diaz,
- Martin Javors,
- William H. Wood 3rd,
- Yongqing Zhang,
- Kevin G. Becker
- Published: January 7, 2014
- https://doi.org/10.1371/journal.pone.0083988