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Research Article

Discovering Subgroups of Patients from DNA Copy Number Data Using NMF on Compacted Matrices

  • Cassio P. de Campos mail,

    cassio@idsia.ch

    Affiliations: Dalle Molle Institute for Artificial Intelligence (IDSIA), Manno, Switzerland, Lymphoma and Genomics Research Program, Institute of Oncology Research (IOR), Bellinzona, Switzerland

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  • Paola M. V. Rancoita,

    Affiliations: Dalle Molle Institute for Artificial Intelligence (IDSIA), Manno, Switzerland, Lymphoma and Genomics Research Program, Institute of Oncology Research (IOR), Bellinzona, Switzerland, University Centre of Statistics for Biomedical Sciences (CUSSB), Vita-Salute San Raffaele University, Milan, Italy

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  • Ivo Kwee,

    Affiliations: Dalle Molle Institute for Artificial Intelligence (IDSIA), Manno, Switzerland, Lymphoma and Genomics Research Program, Institute of Oncology Research (IOR), Bellinzona, Switzerland, Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland

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  • Emanuele Zucca,

    Affiliation: Lymphoma Unit, Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland

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  • Marco Zaffalon,

    Affiliation: Dalle Molle Institute for Artificial Intelligence (IDSIA), Manno, Switzerland

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  • Francesco Bertoni

    Affiliations: Lymphoma and Genomics Research Program, Institute of Oncology Research (IOR), Bellinzona, Switzerland, Lymphoma Unit, Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland

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  • Published: November 20, 2013
  • DOI: 10.1371/journal.pone.0079720

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