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Research Article

NGF Upregulates the Plasminogen Activation Inhibitor-1 in Neurons via the Calcineurin/NFAT Pathway and the Down Syndrome-Related Proteins DYRK1A and RCAN1 Attenuate This Effect

  • Georgios C. Stefos mail,

    stegi121@yahoo.gr

    Affiliations: Institute of Pharmacology and Toxicology, Medical Faculty of the RWTH Aachen University, Aachen, Germany, Systems Biology Programme, Center for Genomic Regulation; Pompeu Fabra University, and Centro de Investigación Biomédica en Red de Enfermedades Raras, Barcelona, Spain

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  • Ulf Soppa,

    Affiliation: Institute of Pharmacology and Toxicology, Medical Faculty of the RWTH Aachen University, Aachen, Germany

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  • Mara Dierssen,

    Affiliation: Systems Biology Programme, Center for Genomic Regulation; Pompeu Fabra University, and Centro de Investigación Biomédica en Red de Enfermedades Raras, Barcelona, Spain

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  • Walter Becker

    Affiliation: Institute of Pharmacology and Toxicology, Medical Faculty of the RWTH Aachen University, Aachen, Germany

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  • Published: June 25, 2013
  • DOI: 10.1371/journal.pone.0067470

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