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Open Access
Peer-reviewed
Research Article
Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry
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Michael J. Kluk,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Todd Ashworth,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Hongfang Wang,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Birgit Knoechel,
Affiliation Departments of Pediatric Hematology/Oncology and Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
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Emily F. Mason,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Elizabeth A. Morgan,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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David Dorfman,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Geraldine Pinkus,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Oliver Weigert,
Affiliation Departments of Pediatric Hematology/Oncology and Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
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Jason L. Hornick,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Lucian R. Chirieac,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Michelle Hirsch,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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David J. Oh,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Andrew P. South,
Affiliation Division of Cancer Research and Genetics Core Services Unit, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
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Irene M. Leigh,
Affiliation Division of Cancer Research and Genetics Core Services Unit, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
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Celine Pourreyron,
Affiliation Division of Cancer Research and Genetics Core Services Unit, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
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Andrew J. Cassidy,
Affiliation Division of Cancer Research and Genetics Core Services Unit, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
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Daniel J. DeAngelo,
Affiliation Departments of Pediatric Hematology/Oncology and Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
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David M. Weinstock,
Affiliation Departments of Pediatric Hematology/Oncology and Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
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Ian E. Krop,
Affiliation Departments of Pediatric Hematology/Oncology and Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
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Deborah Dillon,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Jane E. Brock,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Alexander J. F. Lazar,
Affiliation Department of Pathology, M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Myron Peto,
Affiliation Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America
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Raymond J. Cho,
Affiliation Department of Dermatology, University of California, San Francisco, San Francisco, California, United States of America
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Alexander Stoeck,
Affiliation Merck Oncology, Boston, Massachusetts, United States of America
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Brian B. Haines,
Affiliation Merck Oncology, Boston, Massachusetts, United States of America
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Sriram Sathayanrayanan,
Affiliation Merck Oncology, Boston, Massachusetts, United States of America
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Scott Rodig,
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Jon C. Aster
* E-mail: jaster@rics.bwh.harvard.edu
Affiliation Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry
- Michael J. Kluk,
- Todd Ashworth,
- Hongfang Wang,
- Birgit Knoechel,
- Emily F. Mason,
- Elizabeth A. Morgan,
- David Dorfman,
- Geraldine Pinkus,
- Oliver Weigert,
- Jason L. Hornick
- Published: June 18, 2013
- https://doi.org/10.1371/journal.pone.0067306