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Research Article

Efficacy of a Marine Bacterial Nuclease against Biofilm Forming Microorganisms Isolated from Chronic Rhinosinusitis

  • Robert C. Shields,

    Affiliation: School of Dental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom

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  • Norehan Mokhtar,

    Affiliations: School of Dental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia

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  • Michael Ford,

    Affiliation: Microbiology Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom

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  • Michael J. Hall,

    Affiliation: School of Chemistry, Newcastle University, Newcastle upon Tyne, United Kingdom

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  • J. Grant Burgess,

    Affiliation: School of Marine Science and Technology, Newcastle University, Newcastle upon Tyne, United Kingdom

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  • Mohamed Reda ElBadawey,

    Affiliations: Department of Otolaryngology and Head & Neck Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom, Otolaryngology Department, Tanta University, Tanta, Egypt

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  • Nicholas S. Jakubovics mail

    nick.jakubovics@ncl.ac.uk

    Affiliation: School of Dental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom

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  • Published: February 18, 2013
  • DOI: 10.1371/journal.pone.0055339

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