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Research Article

DNA Methylation in the Neuropeptide S Receptor 1 (NPSR1) Promoter in Relation to Asthma and Environmental Factors

  • Lovisa E. Reinius,

    Affiliations: Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Anna Gref,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Annika Sääf,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Nathalie Acevedo,

    Affiliations: Department of Medicine Solna, Translational Immunology Unit, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Maaike Joerink,

    Affiliations: Department of Medicine Solna, Translational Immunology Unit, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Maciej Kupczyk,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Mauro D'Amato,

    Affiliations: Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Anna Bergström,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Erik Melén,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Annika Scheynius,

    Affiliations: Department of Medicine Solna, Translational Immunology Unit, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Sven-Erik Dahlén,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • The BIOAIR Study Group,

    Membership of the BIOAIR study group is provided in the Acknowledgments.

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  • Göran Pershagen,

    Affiliations: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Cilla Söderhäll,

    Affiliations: Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Juha Kere mail

    juha.kere@ki.se

    Affiliations: Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden, Research Programs Unit, Biomedicum, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden

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  • Published: January 23, 2013
  • DOI: 10.1371/journal.pone.0053877

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