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Research Article

Computational Modeling of Glucose Transport in Pancreatic β-Cells Identifies Metabolic Thresholds and Therapeutic Targets in Diabetes

  • Camilla Luni,

    Affiliations: Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America, Sansum Diabetes Research Institute, Santa Barbara, California, United States of America

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  • Jamey D. Marth,

    Affiliation: Center for Nanomedicine, Sanford-Burnham Medical Research Institute and the Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Francis J. Doyle III mail

    frank.doyle@icb.ucsb.edu

    Affiliations: Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America, Sansum Diabetes Research Institute, Santa Barbara, California, United States of America

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  • Published: December 27, 2012
  • DOI: 10.1371/journal.pone.0053130

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