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Research Article

The LEGSKO Mouse: A Mouse Model of Age-Related Nuclear Cataract Based on Genetic Suppression of Lens Glutathione Synthesis

  • Xingjun Fan mail,

    xxf3@cwru.edu (XF); vmm3@case.edu (VMM)

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Xiaoqin Liu,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Shuyu Hao,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Benlian Wang,

    Affiliation: Case Center for Proteomics and Mass Spectrometry, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Michael L. Robinson,

    Affiliation: Department of Zoology, Miami University, Oxford, Ohio, United States of America

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  • Vincent M. Monnier mail

    xxf3@cwru.edu (XF); vmm3@case.edu (VMM)

    Affiliations: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Published: November 30, 2012
  • DOI: 10.1371/journal.pone.0050832

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