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Research Article

Cerebrospinal Fluid Matrix Metalloproteinases Are Elevated in Cerebral Adrenoleukodystrophy and Correlate with MRI Severity and Neurologic Dysfunction

  • Kathryn A. Thibert,

    Affiliation: Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Gerald V. Raymond,

    Affiliation: Department of Neurogenetics, Kennedy Krieger Institute, Baltimore, Maryland, United States of America

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  • David R. Nascene,

    Affiliation: Department of Radiology, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Weston P. Miller,

    Affiliation: Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Jakub Tolar,

    Affiliation: Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Paul J. Orchard,

    Affiliation: Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Troy C. Lund mail

    lundx072@umn.edu

    Affiliation: Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Published: November 21, 2012
  • DOI: 10.1371/journal.pone.0050430

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