Research Article

High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation

  • Audrey D. McConnell,
  • Minjee Do,
  • Tamlyn Y. Neben,
  • Vladimir Spasojevic,
  • Josh MacLaren,
  • Andy P. Chen,
  • Laurence Altobell III,
  • John L. Macomber,
  • Ashley D. Berkebile,
  • Robert A. Horlick,
  • Peter M. Bowers mail,

    Affiliation: AnaptysBio, Inc., San Diego, California, United States of America

  • David J. King
  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049458

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