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Research Article

Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU

  • Andrei S. Halavaty,

    Affiliations: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America, Center for Structural Genomics of Infectious Diseases (CSGID), Chicago, Illinois, United States of America

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  • Dominika Borek,

    Affiliations: Center for Structural Genomics of Infectious Diseases (CSGID), Chicago, Illinois, United States of America, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Gregory H. Tyson,

    Affiliation: Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Jeff L. Veesenmeyer,

    Affiliation: Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

    Current address: Department of Bacteriology, University of Wisconsin at Madison, Madison, Wisconsin, United States of America

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  • Ludmilla Shuvalova,

    Affiliations: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America, Center for Structural Genomics of Infectious Diseases (CSGID), Chicago, Illinois, United States of America

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  • George Minasov,

    Affiliations: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America, Center for Structural Genomics of Infectious Diseases (CSGID), Chicago, Illinois, United States of America

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  • Zbyszek Otwinowski,

    Affiliations: Center for Structural Genomics of Infectious Diseases (CSGID), Chicago, Illinois, United States of America, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Alan R. Hauser equal contributor,

    equal contributor Contributed equally to this work with: Alan R. Hauser, Wayne F. Anderson

    Affiliation: Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Wayne F. Anderson equal contributor mail

    equal contributor Contributed equally to this work with: Alan R. Hauser, Wayne F. Anderson

    wf-anderson@northwestern.edu.

    Affiliations: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America, Center for Structural Genomics of Infectious Diseases (CSGID), Chicago, Illinois, United States of America

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049388

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