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Research Article

Lysosomotropic Properties of Weakly Basic Anticancer Agents Promote Cancer Cell Selectivity In Vitro

  • Rosemary A. Ndolo,

    Affiliation: Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas, United States of America

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  • Yepeng Luan,

    Affiliation: Institute of Medicinal Chemistry, Shandong University, Jinan, Shandong, China

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  • Shaofeng Duan,

    Affiliation: Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas, United States of America

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  • M. Laird Forrest,

    Affiliation: Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas, United States of America

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  • Jeffrey P. Krise mail

    krise@ku.edu

    Affiliation: Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas, United States of America

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  • Published: November 07, 2012
  • DOI: 10.1371/journal.pone.0049366

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