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Research Article

Suprabasin Is Hypomethylated and Associated with Metastasis in Salivary Adenoid Cystic Carcinoma

  • Chunbo Shao,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Marietta Tan,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Justin A. Bishop,

    Affiliation: Department of Surgical Pathology, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Jia Liu,

    Affiliation: University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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  • Weiliang Bai,

    Affiliation: Department of Otorhinolaryngology, Shengjing Hospital, China Medical University, Shenyang, China

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  • Daria A. Gaykalova,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Takenori Ogawa,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, Tohoku University School of Medicine, Sendai, Miyagi, Japan

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  • Ami R. Vikani,

    Affiliation: The George Washington University School of Medicine, Washington D.C., United States of America

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  • Yuri Agrawal,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Ryan J. Li,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Myoung Sook Kim,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • William H. Westra,

    Affiliation: Department of Surgical Pathology, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • David Sidransky,

    Affiliation: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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  • Joseph A. Califano,

    Affiliations: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Milton J Dance Jr. Head and Neck Center at the Greater Baltimore Medical Center, Baltimore, Maryland, United States of America

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  • Patrick K. Ha mail

    *pha1@jhmi.edu

    Affiliations: Department of Otolaryngology-Head and Neck Surgery, the Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Milton J Dance Jr. Head and Neck Center at the Greater Baltimore Medical Center, Baltimore, Maryland, United States of America

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  • Published: November 07, 2012
  • DOI: 10.1371/journal.pone.0048582

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