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Research Article

Activation of Haem-Oxidized Soluble Guanylyl Cyclase with BAY 60-2770 in Human Platelets Lead to Overstimulation of the Cyclic GMP Signaling Pathway

  • Camila B. Mendes-Silverio,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Luiz O. S. Leiria,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Rafael P. Morganti,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Gabriel F. Anhê,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Sisi Marcondes,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Fabíola Z. Mónica,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Gilberto De Nucci,

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Edson Antunes mail

    edson.antunes@uol.com.br

    Affiliation: Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pone.0047223

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