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Research Article

Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116

  • Fengyan Jin equal contributor,

    equal contributor Contributed equally to this work with: Fengyan Jin, Huifan Ji, Chunshu Jia

    Affiliations: The First Hospital of Jilin University, Changchun, China, Jilin Province Tumor Hospital, Changchun, China, Department of Neurology, University Hospital Essen, Essen, Germany

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  • Huifan Ji equal contributor,

    equal contributor Contributed equally to this work with: Fengyan Jin, Huifan Ji, Chunshu Jia

    Affiliation: The First Hospital of Jilin University, Changchun, China

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  • Chunshu Jia equal contributor,

    equal contributor Contributed equally to this work with: Fengyan Jin, Huifan Ji, Chunshu Jia

    Affiliation: The First Hospital of Jilin University, Changchun, China

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  • Ulf Brockmeier,

    Affiliation: Department of Physiology, University of Duisburg-Essen, Essen, Germany

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  • Dirk M. Hermann,

    Affiliation: Department of Neurology, University Hospital Essen, Essen, Germany

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  • Eric Metzen,

    Affiliation: Department of Physiology, University of Duisburg-Essen, Essen, Germany

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  • Yingqiao Zhu mail,

    chibr@jlu.edu.cn (BC); zhuyingqiaoZYQ@163.com (YZ)

    Affiliation: The First Hospital of Jilin University, Changchun, China

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  • Baorong Chi mail

    chibr@jlu.edu.cn (BC); zhuyingqiaoZYQ@163.com (YZ)

    Affiliation: The First Hospital of Jilin University, Changchun, China

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  • Published: October 10, 2012
  • DOI: 10.1371/journal.pone.0047161

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