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Research Article

Altered Plasma Apolipoprotein Modifications in Patients with Pancreatic Cancer: Protein Characterization and Multi-Institutional Validation

  • Kazufumi Honda,

    Affiliation: Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, Tokyo, Japan

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  • Takuji Okusaka,

    Affiliation: Hepatobiliary and Pancreatic Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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  • Klaus Felix,

    Affiliation: Department of Surgery, University of Heidelberg, Heidelberg, Germany

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  • Shoji Nakamori,

    Affiliation: Department of Surgery, Osaka National Hospital, National Hospital Organization, Osaka, Japan

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  • Naohiro Sata,

    Affiliation: Department of Surgery, Jichi Medical University, Shimotsuke, Japan

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  • Hideo Nagai,

    Affiliation: Department of Surgery, Jichi Medical University, Shimotsuke, Japan

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  • Tatsuya Ioka,

    Affiliation: Department of Hepatobiliary and Pancreatic Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan

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  • Akihiko Tsuchida,

    Affiliation: Third Department of Surgery, Tokyo Medical University, Tokyo, Japan

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  • Takeshi Shimahara,

    Affiliation: Department of Oral Surgery, Osaka Medical College, Osaka, Japan

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  • Masashi Shimahara,

    Affiliation: Department of Oral Surgery, Osaka Medical College, Osaka, Japan

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  • Yohichi Yasunami,

    Affiliation: Department of Regenerative Medicine and Transplantation, Fukuoka University Faculty of Medicine, Fukuoka, Japan

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  • Hideya Kuwabara,

    Affiliation: BioBusiness Group, Mitsui Knowledge Industry, Tokyo, Japan

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  • Tomohiro Sakuma,

    Affiliation: BioBusiness Group, Mitsui Knowledge Industry, Tokyo, Japan

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  • Yoshihiko Otsuka,

    Affiliation: Pancreatic Cancer Diagnosis Project, Molecuence Corporation, Yokohama, Japan

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  • Norihito Ota,

    Affiliation: Pancreatic Cancer Diagnosis Project, Molecuence Corporation, Yokohama, Japan

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  • Miki Shitashige,

    Affiliation: Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, Tokyo, Japan

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  • Tomoo Kosuge,

    Affiliation: Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan

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  • Markus W. Büchler,

    Affiliation: Department of Surgery, University of Heidelberg, Heidelberg, Germany

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  • Tesshi Yamada mail

    tyamada@ncc.go.jp

    Affiliation: Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, Tokyo, Japan

    X
  • Published: October 08, 2012
  • DOI: 10.1371/journal.pone.0046908

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