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Research Article

Inhibition of Xanthine Oxidase by Allopurinol Prevents Skeletal Muscle Atrophy: Role of p38 MAPKinase and E3 Ubiquitin Ligases

  • Frederic Derbre equal contributor,

    equal contributor Contributed equally to this work with: Frederic Derbre, Beatriz Ferrando, Mari Carmen Gomez-Cabrera

    Affiliation: Laboratory “Movement Sport and Health Sciences”, University Rennes 2-ENS Cachan, Rennes, France

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  • Beatriz Ferrando equal contributor,

    equal contributor Contributed equally to this work with: Frederic Derbre, Beatriz Ferrando, Mari Carmen Gomez-Cabrera

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

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  • Mari Carmen Gomez-Cabrera equal contributor,

    equal contributor Contributed equally to this work with: Frederic Derbre, Beatriz Ferrando, Mari Carmen Gomez-Cabrera

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

    X
  • Fabian Sanchis-Gomar,

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

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  • Vladimir E. Martinez-Bello,

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

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  • Gloria Olaso-Gonzalez,

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

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  • Ana Diaz,

    Affiliation: UCIM, Faculty of Medicine, University of Valencia, Valencia, Spain

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  • Arlette Gratas-Delamarche,

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

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  • Miguel Cerda,

    Affiliation: Department of Pathology, University of Valencia, Valencia, Spain

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  • Jose Viña mail

    jose.vina@uv.es

    Affiliation: Department of Physiology, University of Valencia, Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia, Spain

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  • Published: October 05, 2012
  • DOI: 10.1371/journal.pone.0046668

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