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Research Article

The Primacy of β1 Integrin Activation in the Metastatic Cascade

  • Hisashi Kato,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Zhongji Liao,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • John V. Mitsios,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Huan-You Wang,

    Affiliations: Moores UCSD Cancer Center, University of California San Diego, La Jolla, California, United States of America, Department of Pathology, Moores UCSD Cancer Center, University of California San Diego, La Jolla, California, United States of America

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  • Elena I. Deryugina,

    Affiliation: Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Judith A. Varner,

    Affiliations: Department of Medicine, University of California San Diego, La Jolla, California, United States of America, Moores UCSD Cancer Center, University of California San Diego, La Jolla, California, United States of America

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  • James P. Quigley,

    Affiliation: Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Sanford J. Shattil mail

    sshattil@ucsd.edu

    Affiliations: Department of Medicine, University of California San Diego, La Jolla, California, United States of America, Moores UCSD Cancer Center, University of California San Diego, La Jolla, California, United States of America

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  • Published: October 03, 2012
  • DOI: 10.1371/journal.pone.0046576

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