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Research Article

Rare and Low Frequency Variant Stratification in the UK Population: Description and Impact on Association Tests

  • Marie-Claude Babron,

    Affiliations: Inserm UMRS-946, Genetic variability and human diseases, Paris, France, Institut Universitaire d'Hématologie, Univ Paris Diderot, Paris, France

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  • Marie de Tayrac,

    Affiliations: Inserm UMRS-946, Genetic variability and human diseases, Paris, France, Institut Universitaire d'Hématologie, Univ Paris Diderot, Paris, France

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  • Douglas N. Rutledge,

    Affiliation: AgroParisTech, Paris, France

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  • Eleftheria Zeggini equal contributor,

    equal contributor Contributed equally to this work with: Eleftheria Zeggini, Emmanuelle Génin

    Affiliation: Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

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  • Emmanuelle Génin equal contributor mail

    equal contributor Contributed equally to this work with: Eleftheria Zeggini, Emmanuelle Génin

    emmanuelle.genin@inserm.fr

    Affiliations: Inserm UMRS-946, Genetic variability and human diseases, Paris, France, Institut Universitaire d'Hématologie, Univ Paris Diderot, Paris, France

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  • Published: October 05, 2012
  • DOI: 10.1371/journal.pone.0046519

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