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Research Article

Low-Dose Oral Sirolimus and the Risk of Menstrual-Cycle Disturbances and Ovarian Cysts: Analysis of the Randomized Controlled SUISSE ADPKD Trial

  • Matthias Braun,

    Affiliation: Division of Nephrology, University Hospital, Zürich, Switzerland

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  • James Young,

    Affiliation: Biometrical Practice BIOP AG, Basel, Switzerland

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  • Cäcilia S. Reiner,

    Affiliation: Division of Diagnostic and Interventional Radiology, University Hospital, Zürich, Switzerland

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  • Diane Poster,

    Affiliation: Division of Nephrology, University Hospital, Zürich, Switzerland

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  • Fabienne Krauer,

    Affiliation: Division of Nephrology, University Hospital, Zürich, Switzerland

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  • Andreas D. Kistler,

    Affiliation: Division of Nephrology, University Hospital, Zürich, Switzerland

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  • Paulus Kristanto,

    Affiliation: Medication Adherence Research Centre, AARDEX Group, Visé, Belgium

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  • Xueqi Wang,

    Affiliation: Department of Nephrology, Changzheng Hospital, Shanghai, China

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  • Yang Liu,

    Affiliation: Center for Integrative Human Research, University of Zürich, Zürich, Switzerland

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  • Johannes Loffing,

    Affiliation: Institute of Anatomy, University of Zürich, Zürich, Switzerland

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  • Gustav Andreisek,

    Affiliation: Division of Diagnostic and Interventional Radiology, University Hospital, Zürich, Switzerland

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  • Arnold von Eckardstein,

    Affiliation: Institute of Clinical Chemistry, University Hospital, Zürich, Switzerland

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  • Oliver Senn,

    Affiliation: Institute of General Practice and Health Services Research, University Hospital, Zürich, Switzerland

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  • Rudolf P. Wüthrich,

    Affiliation: Division of Nephrology, University Hospital, Zürich, Switzerland

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  • Andreas L. Serra mail

    andreas.serra@usz.ch

    Affiliation: Division of Nephrology, University Hospital, Zürich, Switzerland

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  • Published: October 10, 2012
  • DOI: 10.1371/journal.pone.0045868

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