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Research Article

The Genomic Landscape of TP53 and p53 Annotated High Grade Ovarian Serous Carcinomas from a Defined Founder Population Associated with Patient Outcome

  • Paulina M. Wojnarowicz,

    Affiliation: Department of Human Genetics, McGill University, Montreal, Quebec, Canada

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  • Kathleen Klein Oros,

    Affiliation: Division of Clinical Epidemiology and Segal Cancer Centre, Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada

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  • Michael C. J. Quinn,

    Affiliation: Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Institut du Cancer de Montréal, Montreal, Quebec, Canada

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  • Suzanna L. Arcand,

    Affiliation: The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec, Canada

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  • Karen Gambaro,

    Affiliation: Department of Human Genetics, McGill University, Montreal, Quebec, Canada

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  • Jason Madore,

    Affiliation: Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Institut du Cancer de Montréal, Montreal, Quebec, Canada

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  • Ashley H. Birch,

    Affiliation: Department of Human Genetics, McGill University, Montreal, Quebec, Canada

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  • Manon de Ladurantaye,

    Affiliation: Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Institut du Cancer de Montréal, Montreal, Quebec, Canada

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  • Kurosh Rahimi,

    Affiliation: Department of Pathology, Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, Quebec, Canada

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  • Diane M. Provencher,

    Affiliations: Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Institut du Cancer de Montréal, Montreal, Quebec, Canada, Division of Gynecologic Oncology, Université de Montréal, Montreal, Quebec, Canada

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  • Anne-Marie Mes-Masson,

    Affiliations: Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Institut du Cancer de Montréal, Montreal, Quebec, Canada, Department of Medicine, Université de Montréal, Montreal, Quebec, Canada

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  • Celia M. T. Greenwood,

    Affiliations: Division of Clinical Epidemiology and Segal Cancer Centre, Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada, Department of Oncology, McGill University, Montreal, Quebec, Canada, Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada

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  • Patricia N. Tonin mail

    patricia.tonin@mcgill.ca

    Affiliations: Department of Human Genetics, McGill University, Montreal, Quebec, Canada, The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec, Canada, Department of Medicine, McGill University, Montreal, Quebec, Canada

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  • Published: September 20, 2012
  • DOI: 10.1371/journal.pone.0045484

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