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Research Article

Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10-Producing Regulatory B Cells and High BAFF Levels

  • Anne Saussine,

    Affiliations: INSERM U976, Paris, France, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Immunology, Dermatology & Oncology, UMR-S 976, Paris, France, Service de Dermatologie, Hôpital Saint Louis, Paris, France

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  • Abdellatif Tazi,

    Affiliation: Université Paris Diderot, Sorbonne Paris Cité; AP-HP; Service de Pneumologie, Hôpital Saint Louis, Paris, France

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  • Séverine Feuillet,

    Affiliation: Université Paris Diderot, Sorbonne Paris Cité; AP-HP; Service de Pneumologie, Hôpital Saint Louis, Paris, France

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  • Michel Rybojad,

    Affiliation: Service de Dermatologie, Hôpital Saint Louis, Paris, France

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  • Caroline Juillard,

    Affiliation: Service de Dermatologie, Hôpital Saint Louis, Paris, France

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  • Anne Bergeron,

    Affiliation: Université Paris Diderot, Sorbonne Paris Cité; AP-HP; Service de Pneumologie, Hôpital Saint Louis, Paris, France

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  • Valérie Dessirier,

    Affiliations: INSERM U976, Paris, France, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Immunology, Dermatology & Oncology, UMR-S 976, Paris, France

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  • Fatiha Bouhidel,

    Affiliations: Service d’Anatomopathologie, Hôpital Saint Louis, Paris, France, Université Paris Diderot Sorbonne Paris Cité, Laboratory of Pahology, UMR-S 728, Paris, France

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  • Anne Janin,

    Affiliations: Service d’Anatomopathologie, Hôpital Saint Louis, Paris, France, Université Paris Diderot Sorbonne Paris Cité, Laboratory of Pahology, UMR-S 728, Paris, France

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  • Armand Bensussan mail,

    jean-david.bouaziz@sls.aphp.fr (JB); Armand.Bensussan@inserm.fr (AB)

    Affiliations: INSERM U976, Paris, France, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Immunology, Dermatology & Oncology, UMR-S 976, Paris, France

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  • Martine Bagot equal contributor,

    equal contributor Contributed equally to this work with: Martine Bagot, Jean-David Bouaziz

    Affiliations: INSERM U976, Paris, France, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Immunology, Dermatology & Oncology, UMR-S 976, Paris, France, Service de Dermatologie, Hôpital Saint Louis, Paris, France

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  • Jean-David Bouaziz equal contributor mail

    equal contributor Contributed equally to this work with: Martine Bagot, Jean-David Bouaziz

    jean-david.bouaziz@sls.aphp.fr (JB); Armand.Bensussan@inserm.fr (AB)

    Affiliations: INSERM U976, Paris, France, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Immunology, Dermatology & Oncology, UMR-S 976, Paris, France, Service de Dermatologie, Hôpital Saint Louis, Paris, France

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  • Published: August 22, 2012
  • DOI: 10.1371/journal.pone.0043588

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