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Open Access
Peer-reviewed
Research Article
A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation
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Michelle L. Scalley-Kim,
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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Bruce W. Hess,
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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Ryan L. Kelly,
Affiliation Department of Protein Sciences, VLST Corporation, Seattle, Washington, United States of America
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Anne-Rachel F. Krostag,
Current address: Department of Molecular Networks, Allen Institute for Brain Science, Seattle, Washington, United States of America
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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Kurt H. Lustig,
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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John S. Marken,
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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Pamela J. Ovendale,
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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Aaron R. Posey,
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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Pamela J. Smolak,
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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Janelle D. L. Taylor,
Current address: Department of Research, Oncothyreon Inc., Seattle, Washington, United States of America
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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C. L. Wood,
Current address: Department of Discovery Research, Omeros Corporation, Seattle, Washington, United States of America
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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David L. Bienvenue,
Affiliation Department of Protein Sciences, VLST Corporation, Seattle, Washington, United States of America
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Peter Probst,
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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Ruth A. Salmon,
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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Daniel S. Allison,
Current address: Department of Antibody Technologies, Alder Biopharmaceuticals Inc., Bothell, Washington, United States of America
Affiliation Department of Protein Engineering, VLST Corporation, Seattle, Washington, United States of America
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Teresa M. Foy ,
* E-mail: tfoy@vlstcorp.com
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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Carol J. Raport
Affiliation Department of Immunology and Preclinical Pharmacology, VLST Corporation, Seattle, Washington, United States of America
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A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation
- Michelle L. Scalley-Kim,
- Bruce W. Hess,
- Ryan L. Kelly,
- Anne-Rachel F. Krostag,
- Kurt H. Lustig,
- John S. Marken,
- Pamela J. Ovendale,
- Aaron R. Posey,
- Pamela J. Smolak,
- Janelle D. L. Taylor
- Published: August 17, 2012
- https://doi.org/10.1371/journal.pone.0043332