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Research Article

GUCY2C Opposes Systemic Genotoxic Tumorigenesis by Regulating AKT-Dependent Intestinal Barrier Integrity

  • Jieru Egeria Lin equal contributor,

    equal contributor Contributed equally to this work with: Jieru Egeria Lin, Adam Eugene Snook, Peng Li

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Adam Eugene Snook equal contributor,

    equal contributor Contributed equally to this work with: Jieru Egeria Lin, Adam Eugene Snook, Peng Li

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Peng Li equal contributor,

    equal contributor Contributed equally to this work with: Jieru Egeria Lin, Adam Eugene Snook, Peng Li

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Brian Arthur Stoecker,

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Gilbert Won Kim,

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Michael Sullivan Magee,

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Alex Vladimir Mejia Garcia,

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Michael Anthony Valentino,

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Terry Hyslop,

    Affiliation: Divison of Biostatistics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Stephanie Schulz,

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Scott Arthur Waldman mail

    Scott.Waldman@Jefferson.edu

    Affiliation: Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Published: February 22, 2012
  • DOI: 10.1371/journal.pone.0031686

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