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Research Article

Isotropic 3D Nuclear Morphometry of Normal, Fibrocystic and Malignant Breast Epithelial Cells Reveals New Structural Alterations

  • Vivek Nandakumar,

    Affiliations: School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, Arizona, United States of America, Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America

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  • Laimonas Kelbauskas,

    Affiliation: Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America

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  • Kathryn F. Hernandez,

    Affiliations: Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America, School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

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  • Kelly M. Lintecum,

    Affiliations: Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America, School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

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  • Patti Senechal,

    Affiliation: Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America

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  • Kimberly J. Bussey,

    Affiliations: Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America, Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

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  • Paul C. W. Davies,

    Affiliation: Department of Physics, Arizona State University, Tempe, Arizona, United States of America

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  • Roger H. Johnson mail,

    roger.h.johnson@asu.edu

    Affiliation: Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America

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  • Deirdre R. Meldrum

    Affiliations: School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, Arizona, United States of America, Center for Biosignatures Discovery Automation, Biodesign Institute, Tempe, Arizona, United States of America

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  • Published: January 05, 2012
  • DOI: 10.1371/journal.pone.0029230

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