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Research Article

Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

  • Justin D. Lathia mail,

    lathiaj@ccf.org (JDL); richj@ccf.org (JNR)

    Affiliation: Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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  • Joseph Gallagher,

    Affiliation: Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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  • Jay T. Myers,

    Affiliation: Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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  • Meizhang Li,

    Affiliation: Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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  • Amit Vasanji,

    Affiliation: Image Processing Core, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

    Current address: ImageIQ, Cleveland, Ohio, United States of America

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  • Roger E. McLendon,

    Affiliation: Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Anita B. Hjelmeland,

    Affiliations: Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Molecular Medicine Program, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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  • Alex Y. Huang,

    Affiliation: Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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  • Jeremy N. Rich mail

    lathiaj@ccf.org (JDL); richj@ccf.org (JNR)

    Affiliations: Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Molecular Medicine Program, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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  • Published: September 22, 2011
  • DOI: 10.1371/journal.pone.0024807

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