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Research Article

Towards a Physiology-Based Measure of Pain: Patterns of Human Brain Activity Distinguish Painful from Non-Painful Thermal Stimulation

  • Justin E. Brown,

    Affiliations: Department of Anesthesia, Stanford University, Palo Alto, California, United States of America, Neurosciences Program, Stanford University, Palo Alto, California, United States of America, Department of Biology and Environmental Science, Simpson College, Indianola, Iowa, United States of America

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  • Neil Chatterjee,

    Affiliations: Department of Anesthesia, Stanford University, Palo Alto, California, United States of America, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Jarred Younger,

    Affiliation: Department of Anesthesia, Stanford University, Palo Alto, California, United States of America

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  • Sean Mackey mail

    smackey@pain.stanford.edu

    Affiliations: Department of Anesthesia, Stanford University, Palo Alto, California, United States of America, Neurosciences Program, Stanford University, Palo Alto, California, United States of America

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  • Published: September 13, 2011
  • DOI: 10.1371/journal.pone.0024124

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