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Open Access
Peer-reviewed
Research Article
Efficient Colonization and Therapy of Human Hepatocellular Carcinoma (HCC) Using the Oncolytic Vaccinia Virus Strain GLV-1h68
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Ivaylo Gentschev ,
Contributed equally to this work with: Ivaylo Gentschev, Meike Müller
Affiliations Genelux Corporation, San Diego Science Center, San Diego, California, United States of America, Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany
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Meike Müller ,
Contributed equally to this work with: Ivaylo Gentschev, Meike Müller
Affiliation Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany
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Marion Adelfinger,
Affiliation Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany
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Stephanie Weibel,
Affiliation Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany
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Friedrich Grummt,
Affiliation Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany
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Martina Zimmermann,
Affiliation Department of Gastroenterology and Hepatology, Medical University Hospital, Tuebingen, Germany
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Michael Bitzer,
Affiliation Department of Gastroenterology and Hepatology, Medical University Hospital, Tuebingen, Germany
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Martin Heisig,
Affiliation Department of Internal Medicine, School of Medicine,Yale University, New Haven, Connecticut, United States of America
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Qian Zhang,
Affiliations Genelux Corporation, San Diego Science Center, San Diego, California, United States of America, Department of Radiation Oncology, Rebecca and John Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, California, United States of America
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Yong A. Yu,
Affiliations Genelux Corporation, San Diego Science Center, San Diego, California, United States of America, Department of Radiation Oncology, Rebecca and John Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, California, United States of America
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Nanhai G. Chen,
Affiliations Genelux Corporation, San Diego Science Center, San Diego, California, United States of America, Department of Radiation Oncology, Rebecca and John Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, California, United States of America
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Jochen Stritzker,
Affiliations Genelux Corporation, San Diego Science Center, San Diego, California, United States of America, Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany
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Ulrich M. Lauer ,
¶These authors also contributed equally to this work.
Affiliation Department of Gastroenterology and Hepatology, Medical University Hospital, Tuebingen, Germany
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Aladar A. Szalay
* E-mail: aaszalay@genelux.com
¶These authors also contributed equally to this work.
Affiliations Genelux Corporation, San Diego Science Center, San Diego, California, United States of America, Department of Biochemistry, University of Wuerzburg, Wuerzburg, Germany, Rudolf Virchow Center for Experimental Biomedicine, University of Wuerzburg, Wuerzburg, Germany, Institute for Molecular Infection Biology, University of Wuerzburg, Wuerzburg, Germany, Department of Radiation Oncology, Rebecca and John Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, California, United States of America
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Efficient Colonization and Therapy of Human Hepatocellular Carcinoma (HCC) Using the Oncolytic Vaccinia Virus Strain GLV-1h68
- Ivaylo Gentschev,
- Meike Müller,
- Marion Adelfinger,
- Stephanie Weibel,
- Friedrich Grummt,
- Martina Zimmermann,
- Michael Bitzer,
- Martin Heisig,
- Qian Zhang,
- Yong A. Yu
- Published: July 11, 2011
- https://doi.org/10.1371/journal.pone.0022069