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Research Article

Functional Tooth Regeneration Using a Bioengineered Tooth Unit as a Mature Organ Replacement Regenerative Therapy

  • Masamitsu Oshima equal contributor,

    equal contributor Contributed equally to this work with: Masamitsu Oshima, Mitsumasa Mizuno

    Affiliation: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Mitsumasa Mizuno equal contributor,

    equal contributor Contributed equally to this work with: Masamitsu Oshima, Mitsumasa Mizuno

    Affiliations: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan, Division of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Miyagi, Japan

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  • Aya Imamura,

    Affiliation: Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Miho Ogawa,

    Affiliations: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan, Organ Technologies Inc., Tokyo, Japan

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  • Masato Yasukawa,

    Affiliation: Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Hiromichi Yamazaki,

    Affiliation: Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Ritsuko Morita,

    Affiliation: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Etsuko Ikeda,

    Affiliation: Division of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Miyagi, Japan

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  • Kazuhisa Nakao,

    Affiliation: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Teruko Takano-Yamamoto,

    Affiliation: Division of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Miyagi, Japan

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  • Shohei Kasugai,

    Affiliation: Oral Implantology and Regenerative Dental Medicine Graduate School, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

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  • Masahiro Saito,

    Affiliations: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan, Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan

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  • Takashi Tsuji mail

    t-tsuji@rs.noda.tus.ac.jp

    Affiliations: Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, Japan, Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan, Organ Technologies Inc., Tokyo, Japan

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  • Published: July 12, 2011
  • DOI: 10.1371/journal.pone.0021531

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