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Research Article

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

  • Fuchou Tang equal contributor,

    equal contributor Contributed equally to this work with: Fuchou Tang, Catalin Barbacioru

    Affiliations: Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom, Biodynamic Optical Imaging Center, School of Life Sciences, Peking University, Beijing, China

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  • Catalin Barbacioru equal contributor,

    equal contributor Contributed equally to this work with: Fuchou Tang, Catalin Barbacioru

    Affiliation: Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America

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  • Ellen Nordman,

    Affiliation: Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America

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  • Siqin Bao,

    Affiliation: Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom

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  • Caroline Lee,

    Affiliation: Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom

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  • Xiaohui Wang,

    Affiliation: Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America

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  • Brian B. Tuch,

    Affiliation: Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America

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  • Edith Heard,

    Affiliation: CNRS UMR3215, INSERM U934, Institut Curie, Paris, France

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  • Kaiqin Lao mail,

    a.surani@gurdon.cam.ac.uk (MAS); kaiqinlao@gmail.com (KL)

    Affiliation: Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America

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  • M. Azim Surani mail

    a.surani@gurdon.cam.ac.uk (MAS); kaiqinlao@gmail.com (KL)

    Affiliation: Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom

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  • Published: June 23, 2011
  • DOI: 10.1371/journal.pone.0021208

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