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Toxicity Testing in the 21st Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways

  • Sudin Bhattacharya,

    Affiliation: Program in Chemical Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, United States of America

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  • Qiang Zhang,

    Affiliation: Program in Chemical Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, United States of America

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  • Paul L. Carmichael,

    Affiliation: Safety and Environmental Assurance Centre, Unilever, Colworth Science Park, Sharnbrook, Bedford, United Kingdom

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  • Kim Boekelheide,

    Affiliation: Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America

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  • Melvin E. Andersen mail

    MAndersen@thehamner.org

    Affiliation: Program in Chemical Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, United States of America

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  • Published: June 20, 2011
  • DOI: 10.1371/journal.pone.0020887
  • Featured in PLOS Collections

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