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Research Article

Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells

  • Matteo Fassan,

    Affiliations: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America, Department of Diagnostic Medicine and Special Therapies, University of Padova, Padova, Italy

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  • Domenico D'Arca,

    Affiliation: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Juraj Letko,

    Affiliation: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Andrea Vecchione,

    Affiliations: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America, Division of Pathology, II Faculty of Medicine, University “La Sapienza,” Ospedale Sant'Andrea, Rome, Italy

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  • Marina P. Gardiman,

    Affiliation: Department of Diagnostic Medicine and Special Therapies, University of Padova, Padova, Italy

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  • Peter McCue,

    Affiliation: Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Bernadette Wildemore,

    Affiliation: Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Massimo Rugge,

    Affiliation: Department of Diagnostic Medicine and Special Therapies, University of Padova, Padova, Italy

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  • Dolores Shupp-Byrne,

    Affiliation: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Leonard G. Gomella,

    Affiliation: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Andrea Morrione,

    Affiliation: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Renato V. Iozzo,

    Affiliation: Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Raffaele Baffa mail

    R_Baffa@mail.jci.tju.edu

    Affiliation: Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    Current address: Global Oncology Division, Sanofi-Aventis, Cambridge, Massachusetts, United States of America

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  • Published: May 06, 2011
  • DOI: 10.1371/journal.pone.0019771

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