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Research Article

An Improved Cerulean Fluorescent Protein with Enhanced Brightness and Reduced Reversible Photoswitching

  • Michele L. Markwardt,

    Affiliation: Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Gert-Jan Kremers,

    Affiliation: Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America

    Current address: Department of Cell Biology, Erasmus Medical Center, Rotterdam, The Netherlands

    X
  • Catherine A. Kraft,

    Affiliation: Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Krishanu Ray,

    Affiliation: Center for Fluorescence Spectroscopy and the Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Paula J. C. Cranfill,

    Affiliation: National High Magnetic Field Laboratory and Department of Biological Science, The Florida State University, Tallahassee, Florida, United States of America

    X
  • Korey A. Wilson,

    Affiliation: National High Magnetic Field Laboratory and Department of Biological Science, The Florida State University, Tallahassee, Florida, United States of America

    X
  • Richard N. Day,

    Affiliation: Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

    X
  • Rebekka M. Wachter,

    Affiliation: Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona United States of America

    X
  • Michael W. Davidson,

    Affiliation: National High Magnetic Field Laboratory and Department of Biological Science, The Florida State University, Tallahassee, Florida, United States of America

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  • Mark A. Rizzo mail

    mrizz001@umaryland.edu

    Affiliation: Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Published: March 29, 2011
  • DOI: 10.1371/journal.pone.0017896

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