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Research Article

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

  • Eriko Koshimizu,

    Affiliations: Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America, Graduate School of Marine Science and Technology, University of Marine Science and Technology, Tokyo, Japan

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  • Shintaro Imamura,

    Affiliation: Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America

    Current address: National Research Institute of Fisheries Science, Yokohama, Japan

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  • Jie Qi,

    Affiliations: Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, Florida, United States of America

    Current address: Ocean University of China, Qingdao, China

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  • Jamal Toure,

    Affiliation: Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Delgado M. Valdez Jr,

    Affiliation: Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, Florida, United States of America

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  • Christopher E. Carr,

    Affiliation: Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Jun-ichi Hanai,

    Affiliation: Division of Nephrology, Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Shuji Kishi mail

    kishi@scripps.edu

    Affiliations: Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, Florida, United States of America

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  • Published: March 30, 2011
  • DOI: 10.1371/journal.pone.0017688

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