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Research Article

Enhanced Neutralization Potency of Botulinum Neurotoxin Antibodies Using a Red Blood Cell-Targeting Fusion Protein

  • Sharad P. Adekar,

    Affiliations: Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, United States of America, Immunome, Inc., Wynnewood, Pennsylvania, United States of America, Augmenta Biologicals, LLC, Wynnewood, Pennsylvania, United States of America

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  • Andrew T. Segan,

    Affiliation: Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, United States of America

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  • Cindy Chen,

    Affiliation: Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, United States of America

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  • Rodney Bermudez,

    Affiliation: Immunome, Inc., Wynnewood, Pennsylvania, United States of America

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  • M. D. Elias,

    Affiliation: Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Bernard H. Selling,

    Affiliation: Impact Biologicals, Inc. Wallingford, Pennsylvania, United States of America

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  • B. P. Kapadnis,

    Affiliation: Department of Microbiology, University of Pune, Pune, India

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  • Lance L. Simpson,

    Affiliation: Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Paul M. Simon mail,

    scott.dessain@gmail.com (SKD); simonpm@augmentabio.com (PMS)

    Affiliation: Augmenta Biologicals, LLC, Wynnewood, Pennsylvania, United States of America

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  • Scott K. Dessain mail

    scott.dessain@gmail.com (SKD); simonpm@augmentabio.com (PMS)

    Affiliation: Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, United States of America

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  • Published: March 02, 2011
  • DOI: 10.1371/journal.pone.0017491

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