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Research Article

Covering Chemical Diversity of Genetically-Modified Tomatoes Using Metabolomics for Objective Substantial Equivalence Assessment

  • Miyako Kusano equal contributor,

    equal contributor Contributed equally to this work with: Miyako Kusano, Henning Redestig

    Affiliation: RIKEN Plant Science Center, Yokohama, Japan

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  • Henning Redestig equal contributor,

    equal contributor Contributed equally to this work with: Miyako Kusano, Henning Redestig

    Affiliation: RIKEN Plant Science Center, Yokohama, Japan

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  • Tadayoshi Hirai,

    Affiliation: Graduate School of Life and Environmental Sciences, Gene Research Center, University of Tsukuba, Tsukuba, Japan

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  • Akira Oikawa,

    Affiliation: RIKEN Plant Science Center, Yokohama, Japan

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  • Fumio Matsuda,

    Affiliation: RIKEN Plant Science Center, Yokohama, Japan

    Current address: Organization of Advanced Sciences and Technology, Kobe University, Kobe, Hyogo, Japan

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  • Atsushi Fukushima,

    Affiliation: RIKEN Plant Science Center, Yokohama, Japan

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  • Masanori Arita,

    Affiliations: RIKEN Plant Science Center, Yokohama, Japan, Department of Biophysics and Biochemistry, The University of Tokyo, Tokyo, Japan

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  • Shin Watanabe,

    Affiliation: Graduate School of Life and Environmental Sciences, Gene Research Center, University of Tsukuba, Tsukuba, Japan

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  • Megumu Yano,

    Affiliation: Graduate School of Life and Environmental Sciences, Gene Research Center, University of Tsukuba, Tsukuba, Japan

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  • Kyoko Hiwasa-Tanase,

    Affiliation: Graduate School of Life and Environmental Sciences, Gene Research Center, University of Tsukuba, Tsukuba, Japan

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  • Hiroshi Ezura,

    Affiliation: Graduate School of Life and Environmental Sciences, Gene Research Center, University of Tsukuba, Tsukuba, Japan

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  • Kazuki Saito mail

    ksaito@psc.riken.jp

    Affiliations: RIKEN Plant Science Center, Yokohama, Japan, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

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  • Published: February 16, 2011
  • DOI: 10.1371/journal.pone.0016989

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