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Research Article

Niclosamide Prevents the Formation of Large Ubiquitin-Containing Aggregates Caused by Proteasome Inhibition

  • Esther Gies equal contributor,

    equal contributor Contributed equally to this work with: Esther Gies, Inga Wilde

    Affiliations: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Inga Wilde equal contributor,

    equal contributor Contributed equally to this work with: Esther Gies, Inga Wilde

    Affiliations: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Jason M. Winget,

    Affiliations: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Maria Brack,

    Affiliations: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Barak Rotblat,

    Affiliations: Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada, Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Carolina Arias Novoa,

    Affiliations: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Aruna D. Balgi,

    Affiliation: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Poul H. Sorensen,

    Affiliations: Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada, Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Michel Roberge,

    Affiliation: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Thibault Mayor mail

    mayor@interchange.ubc.ca

    Affiliations: Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, Centre for High-Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Published: December 23, 2010
  • DOI: 10.1371/journal.pone.0014410

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