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Research Article

β2-Syntrophin Is a Cdk5 Substrate That Restrains the Motility of Insulin Secretory Granules

  • Sandra Schubert,

    Affiliations: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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  • Klaus-Peter Knoch,

    Affiliation: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany

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  • Joke Ouwendijk,

    Affiliation: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany

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  • Shabaz Mohammed,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

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  • Yury Bodrov,

    Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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  • Melanie Jäger,

    Affiliation: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany

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  • Anke Altkrüger,

    Affiliation: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany

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  • Carolin Wegbrod,

    Affiliations: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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  • Marvin E. Adams,

    Affiliation: Department of Physiology and Biophysics, University of Washington, Seattle, Washington, United States of America

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  • Yong Kim,

    Affiliation: Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, United States of America

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  • Stanley C. Froehner,

    Affiliation: Department of Physiology and Biophysics, University of Washington, Seattle, Washington, United States of America

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  • Ole N. Jensen,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

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  • Yannis Kalaidzidis,

    Affiliations: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia

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  • Michele Solimena mail

    michele.solimena@tu-dresden.de

    Affiliations: Molecular Diabetology, Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus at Dresden University of Technology, Dresden, Germany, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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  • Published: September 23, 2010
  • DOI: 10.1371/journal.pone.0012929

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