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Research Article

Transcriptional Regulation of Human and Rat Hepatic Lipid Metabolism by the Grapefruit Flavonoid Naringenin: Role of PPARα, PPARγ and LXRα

  • Jonathan Goldwasser,

    Affiliations: Center for Engineering in Medicine, Shriners Burns Hospital, Boston, Massachusetts, United States of America, Harvard-MIT Division of Health Science and Technology, Cambridge, Massachusetts, United States of America

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  • Pazit Y. Cohen,

    Affiliation: The Selim and Rachel Benin School of Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Eric Yang,

    Affiliations: Center for Engineering in Medicine, Shriners Burns Hospital, Boston, Massachusetts, United States of America, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Patrick Balaguer,

    Affiliation: INSERM, Univ Montpellier I, Montpellier, France

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  • Martin L. Yarmush,

    Affiliations: Center for Engineering in Medicine, Shriners Burns Hospital, Boston, Massachusetts, United States of America, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Yaakov Nahmias mail

    ynahmias@cs.huji.ac.il

    Affiliations: Center for Engineering in Medicine, Shriners Burns Hospital, Boston, Massachusetts, United States of America, The Selim and Rachel Benin School of Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: August 25, 2010
  • DOI: 10.1371/journal.pone.0012399

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