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Open Access
Peer-reviewed
Research Article
Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies
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Katherine S. Elliott,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Eleftheria Zeggini,
Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Applied Statistical Genetics, Wellcome Trust Sanger Institute, University of Cambridge, Cambridge, United Kingdom
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Mark I. McCarthy,
Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom
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Julius Gudmundsson,
Affiliation deCODE Genetics, Reykjavik, Iceland
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Patrick Sulem,
Affiliation deCODE Genetics, Reykjavik, Iceland
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Simon N. Stacey,
Affiliation deCODE Genetics, Reykjavik, Iceland
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Steinunn Thorlacius,
Affiliation deCODE Genetics, Reykjavik, Iceland
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Laufey Amundadottir,
Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
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Henrik Grönberg,
Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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Jianfeng Xu,
Affiliations Center for Cancer Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America, Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
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Valerie Gaborieau,
Affiliation Genetic Epidemiology Group, International Agency for Research on Cancer (IARC), Lyon, France
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Rosalind A. Eeles,
Affiliation Oncogenetics Team, The Institute of Cancer Research, Sutton, United Kingdom
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David E. Neal,
Affiliation Department of Oncology, University of Cambridge, Cambridge, United Kingdom
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Jenny L. Donovan,
Affiliation Department of Social Medicine, University of Bristol, Bristol, United Kingdom
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Freddie C. Hamdy,
Affiliation Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom
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Kenneth Muir,
Affiliation Health Sciences Research Institute, University of Warwick, Coventry, United Kingdom
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Shih-Jen Hwang,
Affiliation Framingham Study, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America
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Margaret R. Spitz,
Affiliation Department of Epidemiology, M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Brent Zanke,
Affiliations Ontario Institute for Cancer Research, MaRS Centre, Toronto, Ontario, Canada, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
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Luis Carvajal-Carmona,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Kevin M. Brown,
Affiliation Integrated Cancer Genomics Division, The Translational Genomics Research Institute, Phoenix, Arizona, United States of America
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Australian Melanoma Family Study Investigators ,
¶See acknowledgments for author list.
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Nicholas K. Hayward,
Affiliation Queensland Institute of Medical Research, Royal Brisbane Hospital, Brisbane, Queensland, Australia
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Stuart Macgregor,
Affiliation Queensland Institute of Medical Research, Royal Brisbane Hospital, Brisbane, Queensland, Australia
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Ian P. M. Tomlinson,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Mathieu Lemire,
Affiliation Ontario Institute for Cancer Research, MaRS Centre, Toronto, Ontario, Canada
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Christopher I. Amos,
Affiliation Department of Epidemiology, M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Joanne M. Murabito,
Affiliation Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
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William B. Isaacs,
Affiliation The Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
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Douglas F. Easton,
Affiliation Cancer Research UK Genetic Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
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Paul Brennan,
Affiliation Genetic Epidemiology Group, International Agency for Research on Cancer (IARC), Lyon, France
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The PanScan Consortium ,
¶See acknowledgments for author list.
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Rosa B. Barkardottir,
Affiliations Department of Pathology, Landspitali-University Hospital of Iceland, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
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Daniel F. Gudbjartsson,
Affiliation deCODE Genetics, Reykjavik, Iceland
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Thorunn Rafnar,
Affiliation deCODE Genetics, Reykjavik, Iceland
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David J. Hunter,
Affiliation Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Stephen J. Chanock,
Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
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Kari Stefansson,
Affiliation deCODE Genetics, Reykjavik, Iceland
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John P. A. Ioannidis
* E-mail: jioannid@cc.uoi.gr
Affiliations Department of Hygiene and Epidemiology, University of Ioannina School of Medicine and Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece, Center for Genetic Epidemiology and Modelling, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies
- Katherine S. Elliott,
- Eleftheria Zeggini,
- Mark I. McCarthy,
- Julius Gudmundsson,
- Patrick Sulem,
- Simon N. Stacey,
- Steinunn Thorlacius,
- Laufey Amundadottir,
- Henrik Grönberg,
- Jianfeng Xu
- Published: May 28, 2010
- https://doi.org/10.1371/journal.pone.0010858